Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

Bringing harmony to Apple’s internal fiefdoms has not been easy. There is still “huge tension” inside Apple, according to one person who has worked with the company for many years. “That tension is something he uses to run the company but it can be dangerous.”
[ei'li:t]
Roula Khalaf
主流网络游戏仍然是大型多人在线角色扮演游戏 (MMORPG)。报告说,今年10月,中国最热门的10款网络游戏中有6款都属于大型多人在线角色扮演游戏。动视暴雪(Activision Blizzard)开发的《魔兽世界》(World of Warcraft)在注册用户和最高同时在线人数方面仍然排名榜首。但报告指出,目前围绕着这款游戏大陆运营权的政府监管纷争可能会给《魔兽世界》带来负面影响。网易公司目前持有《魔兽世界》的中国大陆独家运营权。
[reind?]
The 2017 grads of Tsinghua University earn an average salary of 9,065 yuan per month, according to the survey released by xinchou.cn, an internet salary survey and report provider.
Having longer does not seem to make it easier, however. Proper time management is essential in order to maintain the momentum. “A couple of obligatory projects would help keep the pace and avoid a very intense last quarter,” commented one graduate from Warwick Business School. Overall, the graduates from the class of 2012 took slightly longer than 2.5 years to graduate.
德银资产管理公司(Deutsche AM)亚太区被动型资产管理部门主管马尔科?蒙塔纳里(Marco Montanari)也认为,在亚洲ETF市场迈向更高台阶之前,必须从根本上改革分销制度。
2. 达美乐(Dachis) 品牌喜爱度:-11%/排名:62
年度最佳合唱:埃里克·丘奇、杰森·阿尔丁、卢克布·莱恩《The Only Way I Know》
Recipient: Canadian Prime Minister Justin Trudeau
Jennifer Lawrence also took home the gong for best actress in a movie for her role in the critical darling Joy.
One highlight of last year's box office was seven high-quality domestic films listed on the top 10 earners, including 'Monster Hunt', a live-action hybrid, and 'Monkey King: Hero is Back', a 3D animation based on the classic ancient story.
It set minimum prices too high for commodities including cotton, sugar and corn, and as those prices diverged from the market prices, authorities encouraged excessive production as well as strong import flows.
None of these conditions is in place now. Fed tightening, begun in December, has been put on hold. The federal funds rate (the interbank overnight lending rate) is estimated to be more than a percentage point below its natural level. And there have been no surprises from the Fed. Last December’s 25 basis point rise in the Fed’s policy rate, for example, was comprehensively signalled in advance.
在上月销量最高的SUV和MPV制造商中,大家所熟悉的长城汽车和上汽通用五菱汽车成功卫冕。在轿车和掀背车型上,上汽大众也保持其冠军地位。
Haruhiko Kuroday, the Japanese central bank governor said: “I think we can be cautiously optimistic about the global outlook.
日本央行会收紧货币政策吗?
道·哈德森,学院理事会执行官
She had recently emerged as the right hand of her father, the former Prime Minister Nawaz Sharif. But corruption charges are clouding her rapid rise.
不过,对其他地区的出口却差多了,尤其是对转口地区香港的贸易,该月以美元计的对香港出口同比下滑26.3%至338.4亿美元。对欧盟(EU)国家的出口也下滑4.7%至335亿美元。而对日本出口则下滑5.5%至112.7亿美元。
在中国北方分析出的这种病毒与1957年以前传播的病毒相似,因此,1957年以前出生的人一般都有了抵抗力,而在那年之后出生的儿童和年轻人由于没有预先的免疫力而缺乏抵抗力。1978年这种病毒在世界各地传播开来,其中包括美国。这种病主要发生在孩子们身上,因此,这次流感没被看成是真正的大流行。1977-78年的流感季节,还没有及时地生产出控制病毒的疫苗,但是,1978-79年的流感疫苗就包含了这种病毒的疫苗。
科派斯塔克表示,东京回归榜首并不让人惊讶,因为东京的高工资推动了物价的上涨,房价和房租也很昂贵。
《副总统》(Veep):Netflix公司的热门剧《纸牌屋》(House of Cards)今年露出疲态,但另一部讽刺华盛顿的HBO电视剧《副总统》却在第三季中更上一层楼。塞琳娜(朱莉娅·路易斯-德莱弗斯[Julia Louis-Dreyfus]饰)和助手加里(Gary,托尼·黑尔[Tony Hale]饰)在洗手间里发现自己即将成为总统后,激动得失声大笑,成为2014年喜剧片中最滑稽的一幕。
ex出+panse扩展+ion表名词,“动作或状态 ”→扩张


宝能的“突袭”遭到了万科创始人王石的强烈抵制,后者寻找“白衣骑士”出手相助,迄今为止成功地保住了对这家由管理层主导的企业的控制权。这场收购大战既推动万科在深圳股市的股价大涨,又大幅推升了姚振华的已知财富。
住房市场能轻松适应利率上升吗?
Emily Ratajkowski managed to steal the show, opting for a seriously saucy twist on the classic ballgown. Opting for a semi-sheer lacey black number, the We Are Your Friends actress ensured her world-famous figure was on display.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

10.Selfie Sticks
今年,该学校首次跻身前20强。
Although it looked like the mobile patent wars might cool off after several settlements late in 2014, this year kicked off with a skirmish between Apple and Ericsson over patent royalties related to wireless communications. BlackBerry used to be pretty litigious: It even took on celebrity Ryan Seacrest over its keyboard! But these days it is more focused on trying to convince smartphone buyers that its technology is cool again. Or at least relevant.
一个更大的侧影

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

There should be no more arbitrary use of government power and that requires that the government must no longer overreach itself and we must eliminate any possible room for rent-seeking behaviors. This reform must be persistently pursued by the central government and all local governments at varies levels.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

会。目前有很多利好因素:利润、经济增长和美国减税。但这些都是已知因素。按照历史标准看,眼下股价高得离谱,但这对短期走势毫无参考价值。最终还是要看流动性,自从股市在2009年从危机中走出来以后,流动性始终驱动着股市上涨。如果一切按计划进行,到2018年底,各国央行会在缩表和撤除流动性。如果各央行果真这样做,标普500指数很可能会牛气不再。但只要稍有风吹草动,央行官员们就会迟疑。这股牛气应该会继续。
CEO:作为汽车业新人,通用CEO玛丽o芭拉和福特CEO马克o菲尔兹开始密切观注菲亚特和克莱斯勒集团CEO的塞尔吉奥o马基奥尼的一举一动。虽然他的商业帝国横跨欧美两个大陆,但马基奥尼还是成功地把公司的美国市场份额提高了1.2个点,完全没有受到公司最弱的一条产品线以及八速变速箱问题的影响。

其他地方已经出现了这种情况。
Always wanted to be an author but not sure where to start? Have you considered self-publishing? Thanks to Amazon, you can. Kindle Direct Publishing allows you to get the word out via e-books, CreateSpacehelps you develop a print edition and ACX is the audio publishing division. I’ve used all three to develop my book.
美国国家篮球协会(NBA)近日宣布,NBA全球赛将在中国举办两场金州勇士队对明尼苏达森林狼队的季前赛。
sup在下面+ply重叠,折叠→重叠下去→供应[下去],补给
在全球前50名女富豪中,中国大陆的女企业家占56%。
Paramore, 'After Laughter'

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


“老房奴”减负:20年百万贷款月供可省逾700元


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


“谁来支付由此产生的成本呢?”纽约合作公寓和共管公寓委员会(Council of New York Cooperatives and Condominiums)的主席马克·J·卢森堡(Marc J. Luxemburg)表示,“这会给许多楼盘带来真真切切的成本。”
上海社会科学院的专家周海旺告诉环球时报:“上海自2014以来就采取了一系列强硬措施,包括改造城中村和规范群租来控制人口增长。”
长话短说,1772年圣诞节后,Seppenwolde很快就破产了。这场灾难是当时荷兰报纸的头条新闻。它彻底毁了阿姆斯特丹一批商人和银行家。为了防止出现全面的信贷崩溃,阿姆斯特丹市只能作为最后贷款人暂时介入。这种情形是不是似曾相识?
2013美国就业前景最好的州:亚利桑那州,德州
adj. 肌肉的,肌肉发达的
Jennifer Lawrence also took home the gong for best actress in a movie for her role in the critical darling Joy.
惊险、欢快与不安交替进行,乔纳森·格雷泽导演的非凡之处在于让色情电影难得的实现了幻想与现实的融合。
3. Kate Upton
Targeted poverty alleviation
[in'spekn]

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the adj. 浪漫的 to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

The Magic have bounced between average and bad, and they're currently on a downswing. Now Aaron Gordon and Nikola Vucevic are coming off the bench and Mario Hezonja is buried.
《性别之战》
20. Best Advice for Movie Lovers In August, the scholar Wheeler Winston Dixon sounded an alarm: “If you go on Amazon and you see some great black-and-white film, and it’s going for $3, or any kind of foreign or obscure film, buy it, because it’s going out of print, and they’re not going to put them back into print.” Tens of thousands of films that were on VHS never made the jump to DVD or to Blu-ray, Mr. Dixon warns. And the brave new world of downloads (a.k.a. electronic sell-through) — well, tune in next year.
尤吉利时机恰当和思虑周密的举动应该能扭转猛龙下滑的颓势。

葡萄牙完全使用可再生能源供电四天

  • Only the first three authors are listed, followed by "et al."
  • 尚未开盘房源已卖光 南京一楼盘涉嫌无证预售
  • 地板企业不该过分依赖楼市 质量取胜是关键


我原以为胡扯是失败与庸俗的产物——它的存在是因为真相往往太伤人,或者高管们懒得弄明原委。
Their inclusion has come at the expense mainly of European companies, signalling the shift in economic power towards the east. There is only one Indian brand in the top 100 ranking — HDFC Bank. Russian, Mexican and Brazilian brands have fallen out of the ranking in the past few years — a sober reflection of the changing fortunes of these emerging markets.

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